Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.50 |
| ▸ | HTR2B | P41595 | 5/20 | 0.50 |
| ▸ | HTR2A | P28223 | 4/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.36 |
| ▸ | RAMP1 | O60894 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2100919 | 0.83 | BRD4 (0.50) | HTR2CHTR2BHTR2APARP1BRD4 | |
| SCHEMBL31184549 | 0.83 | BRD4 (0.50) | HTR2CHTR2BHTR2APARP1BRD4 | |
| SCHEMBL31184539 | 0.83 | BRD4 (0.50) | HTR2CHTR2BHTR2APARP1BRD4 | |
| Hydrochloric Acid SCHEMBL1812169 | 0.82 | BRD4 (0.49) | HTR2CHTR2BHTR2APARP1BRD4 | |
| SCHEMBL14417234 | 0.82 | HTR2C (0.43) | HTR2CHTR2BHTR2APARP1KDM4E | |
| SCHEMBL22587762 | 0.82 | OPRM1 (0.45) | HTR2CHTR2BHTR2AOPRM1OPRD1 | |
| SCHEMBL31285933 | 0.82 | OPRM1 (0.45) | HTR2CHTR2BHTR2AOPRM1OPRD1 | |
| SCHEMBL16801723 | 0.82 | OPRM1 (0.65) | HTR2CHTR2BHTR2AOPRM1OPRD1 | |
| SCHEMBL9280480 | 0.78 | HTR2C (0.56) | HTR2CHTR2BHTR2AOPRM1OPRK1 | |
| SCHEMBL3964481 | 0.76 | OPRM1 (0.49) | OPRM1OPRD1OPRK1OGFRL1CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360525-A | NEUROLEPTIC AGENTS, ANTIDEPRESSANTS, SLEEP PROMOTERS | SANDOZ LTD. (CH) | 1982-11-23 | — | — | US | disclosed |