Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.56 |
| ▸ | HTR2A | P28223 | 7/20 | 0.56 |
| ▸ | HTR2B | P41595 | 8/20 | 0.56 |
| ▸ | PARP1 | P09874 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11103752 | 0.81 | HTR2A (0.49) | HTR2CHTR2AHTR2BCYP3A4CYP2C9 | |
| SCHEMBL2210808 | 0.81 | PARP1 (0.49) | HTR2CHTR2AHTR2BPARP1NAMPT | |
| SCHEMBL30658421 | 0.81 | PARP1 (0.49) | HTR2CHTR2AHTR2BPARP1NAMPT | |
| Hydrochloric Acid SCHEMBL3888469 | 0.79 | PARP1 (0.48) | HTR2CHTR2AHTR2BPARP1NAMPT | |
| SCHEMBL11247722 | 0.78 | HTR2C (0.50) | HTR2CHTR2AHTR2BPARP1MEN1 | |
| SCHEMBL11242393 | 0.77 | HTR2C (0.49) | HTR2CHTR2AHTR2BPARP1 | |
| SCHEMBL11247293 | 0.77 | HTR2C (0.49) | HTR2CHTR2AHTR2BPARP1 | |
| SCHEMBL7985474 | 0.77 | HTR2C (0.50) | HTR2CHTR2AHTR2BPARP1HRH3 | |
| SCHEMBL2709111 | 0.77 | HTR2C (0.77) | HTR2CHTR2AHTR2BCYP2D6CHRM2 | |
| Hydrochloric Acid SCHEMBL3947175 | 0.75 | HTR2C (0.75) | HTR2CHTR2AHTR2BCYP2D6CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5461047-A | Analgesics and treats prostaglandin-E2 mediated diseases in animals | G. D. SEARLE & CO. (US) | 1995-10-24 | — | — | US | disclosed |
| US-5354747-A | Analgesics | G. D. SEARLE & CO. (US) | 1994-10-11 | — | — | US | disclosed |
| US-4434171-A | NEUROLEPTIC, ANTIDEPRESSANT | SANDOZ LTD. (CH) | 1984-02-28 | — | — | US | disclosed |