Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10360821 | 0.82 | MAOB (0.49) | MAOBCYP19A1ARSLC6A2SLC6A4 | |
| SCHEMBL6711967 | 0.82 | CYP19A1 (0.45) | MAOBCYP19A1GAAALDH1A1RAB9A | |
| SCHEMBL6700954 | 0.82 | CYP19A1 (0.45) | MAOBCYP19A1ALDH1A1RAB9AKMT2A | |
| SCHEMBL126600 | 0.82 | AR (0.52) | MAOBCYP19A1GAAALDH1A1RAB9A | |
| SCHEMBL11049014 | 0.82 | MAOB (0.49) | MAOBCYP19A1ALDH1A1KMT2A | |
| SCHEMBL10360799 | 0.82 | AR (0.35) | MAOBCYP19A1ALDH1A1RAB9ANPC1 | |
| SCHEMBL126193 | 0.82 | ABCG2 (0.55) | MAOBCYP19A1GAAALDH1A1RAB9A | |
| SCHEMBL11245736 | 0.81 | CYP19A1 (0.46) | MAOBCYP19A1ALDH1A1ALDH2KMT2A | |
| SCHEMBL19746 | 0.81 | CYP19A1 (0.45) | MAOBCYP19A1GAAALDH1A1RAB9A | |
| SCHEMBL10360806 | 0.80 | ALDH1A1 (0.51) | MAOBGAAALDH1A1KMT2AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100384855-C | Poly-substituted flavan zothia dizoline kind compound and preparation process and use thereof | UNIV ZHEJIANG (CN) | 2008-04-30 | — | — | CN | disclosed |
| CN-1793148-A | Poly-substituted flavan zothia dizoline kind compound and preparation process and use thereof | UNIV ZHEJIANG (CN) | 2006-06-28 | — | — | CN | disclosed |
| EP-0025161-B1 | 3-METHYLENE FLAVANONES AND 3-METHYLENE CHROMANONES, ANTIMICROBIAL COMPOSITION CONTAINING SAME AND METHOD OF INHIBITING THE GROWTH OF MICROORGANISMS | MILES LABORATORIES, INC. (US) | 1982-06-09 | — | — | EP | disclosed |
| EP-0025161-A1 | 3-Methylene flavanones and 3-methylene chromanones, antimicrobial composition containing same and method of inhibiting the growth of microorganisms | MILES LABORATORIES, INC. (US) | 1981-03-18 | — | — | EP | disclosed |
| US-4241069-A | MICROBIOCIDES | MILES LABORATORIES, INC. (US) | 1980-12-23 | — | — | US | disclosed |