SCHEMBL126600

SCHEMBL126600

O=C1Cc2cc(O)ccc2OC1c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.52
CYP19A1 P11511 5/20 0.49
MAOA P21397 1/20 0.49
MAOB P27338 1/20 0.49
PSMB5 P28074 1/20 0.49
ESR2 Q92731 4/20 0.45
ESR1 P03372 3/20 0.45
HSD17B10 Q99714 2/20 0.45
ALDH1A1 P00352 1/20 0.45
GAA P10253 1/20 0.45
HPGD P15428 1/20 0.45
CYP3A4 P08684 3/20 0.43
MAPT P10636 3/20 0.41
CYP1A1 P04798 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP1B1 Q16678 1/20 0.41
MEN1 O00255 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27639659 0.91 ESR2 (0.51) ARCYP19A1MAOAMAOBPSMB5
SCHEMBL6848879 0.90 CYP19A1 (0.50) ARCYP19A1MAOAMAOBPSMB5
SCHEMBL13730471 0.88 CYP19A1 (0.49) ARCYP19A1MAOAMAOBPSMB5
SCHEMBL130268 0.88 CYP19A1 (0.49) ARCYP19A1MAOAMAOBPSMB5
SCHEMBL27543000 0.87 ESR2 (0.44) ARCYP19A1MAOAMAOBPSMB5
SCHEMBL27541883 0.86 ESR1 (0.43) ARCYP19A1MAOAMAOBESR2
SCHEMBL6700954 0.85 CYP19A1 (0.45) ARCYP19A1MAOBHSD17B10ALDH1A1
SCHEMBL27542946 0.85 AR (0.41) ARCYP19A1MAOAMAOBPSMB5
SCHEMBL27639658 0.83 FABP5 (0.44) ARMAOAMAOBALDH1A1GAA
SCHEMBL5082125 0.83 AR (0.53) ARCYP19A1MAOAMAOBPSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120078040-A Preparation method of corn flour for corn cauterization production 巢湖美维食品有限公司 2025-06-03 CN claimed
WO-2025091065-A1 FLAVONOID COMPOSITION GRETALS AUSTRALIA PTY LTD (AU) 2025-05-08 WO claimed
CN-117338835-A Preparation method of medicine tablet for treating osteoporosis 广西十万山制药有限公司 2024-01-05 CN claimed
US-20230172901-A1 COMPOSITIONS AND METHODS FOR THE PROPHYLAXIS AND TREATMENT OF FIBROTIC AND INFLAMMATORY CONDITIONS GRETALS AUSTRALIA PTY LTD (AU) 2023-06-08 US claimed
EP-4146194-A1 COMPOSITIONS AND METHODS FOR THE PROPHYLAXIS AND TREATMENT OF FIBROTIC AND INFLAMMATORY CONDITIONS Gretals Australia Pty Ltd (AU) 2023-03-15 EP claimed
WO-2021222987-A1 COMPOSITIONS AND METHODS FOR THE PROPHYLAXIS AND TREATMENT OF FIBROTIC AND INFLAMMATORY CONDITIONS GRETALS AUSTRALIA PTY LTD (AU) 2021-11-11 WO claimed
CN-112471500-A Preparation method of edible fungus tablets for reducing blood pressure and blood fat 当涂县黄池蔬菜产销专业合作社 2021-03-12 CN claimed
CN-112471377-A Preparation method of edible fungus instant drink powder capable of protecting skin and beautifying 当涂县黄池蔬菜产销专业合作社 2021-03-12 CN claimed
CN-111150003-A Preparation method of spicy and hot flavored marinated duck necks 巢湖市金魁食品加工有限公司 2020-05-15 CN claimed
US-20080254519-A1 Process for Producing Picolinic Acid Compounds SHINDO KAZUTOSHI 2008-10-16 US claimed
US-20070160688-A1 Use of flavonoids to increase blood serum levels of dehydroepiandrosterone PROPRIETARY WELLNESS, LLC 2007-07-12 US claimed
EP-1726645-A1 PROCESS FOR PRODUCING PICOLINIC ACID COMPOUNDS MARINE BIOTECHNOLOGY INSTITUTE CO., LTD. (JP) 2006-11-29 EP claimed
US-20040086983-A1 Method for producing a heterocyclic compound and an aromatic carboxylic acid having one or more hydroxyl groups, and modified aromatic ring dioxygenase MARINE BIOTHECHNOLOGY INSTITUTE., LTD. (JP) 2004-05-06 US claimed
US-20260033492-A1 Pest Repellents and Uses Thereof SENSORYGEN INC (US) 2026-02-05 US disclosed
US-20250257336-A1 ISOLATED OR ENGINEERED POLYPEPTIDES, MICROORGANISMS AS WELL AS METHOD FOR SYNTHESIZING POLYPHENOLIC PHYTOCHEMICALS PHOSPHATE DERIVATIVE USING THE POLYPEPTIDES OR MICROORGANISMS UNIV NAT TAIWAN (TW) 2025-08-14 US disclosed
CN-120078040-A Preparation method of corn flour for corn cauterization production 巢湖美维食品有限公司 2025-06-03 CN disclosed
US-4937257-A Flavanone derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1990-06-26 US disclosed
US-4780478-A Aminopropoxy-chromones useful as antidepressants MERCK PATENT GESELLSCHAFT MIT BERSCHRANKTER HAFTUNG (DE) 1988-10-25 US disclosed
US-4508732-A Basic ethers useful as antidepressant agents MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1985-04-02 US disclosed
US-4376123-A Hexahydroazepinyloxy-chromones useful as antidepressants MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1983-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070160688-A1 Use of flavonoids to increase blood serum levels of dehydroepiandrosterone SHBG, CYP17A1, HSD17B11 AR 78/4885CYP19A1 5/4885MAOA 763/4885
US-20260033492-A1 Pest Repellents and Uses Thereof F3, TFPI, FLI1 AR 4093/4885CYP19A1 2958/4885MAOA 602/4885
US-20080254519-A1 Process for Producing Picolinic Acid Compounds HPD, PAH, DHPS AR 1165/4885CYP19A1 126/4885MAOA 187/4885
US-20230172901-A1 COMPOSITIONS AND METHODS FOR THE PROPHYLAXIS AND TREATMENT OF FIBROTIC AND INFLAMMATORY CONDITIONS MMP1, COL1A1, SERPINB1 AR 3364/4885CYP19A1 3035/4885MAOA 2155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.