Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.61 |
| ▸ | SLC22A6 | Q4U2R8 | 3/20 | 0.61 |
| ▸ | SLC22A8 | Q8TCC7 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ESR1 | P03372 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cefatrizine SCHEMBL28000091 | 1.00 | MAPT (0.61) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| Cefatrizine SCHEMBL3688526 | 1.00 | MAPT (0.61) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| Cefatrizine SCHEMBL49503 | 1.00 | MAPT (0.61) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| Cefatrizine SCHEMBL11671021 | 1.00 | MAPT (0.61) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| Cefatrizine SCHEMBL10520664 | 0.99 | MAPT (0.60) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| Cefatrizine SCHEMBL27940222 | 0.98 | MAPT (0.61) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| Cefatrizine SCHEMBL17867569 | 0.98 | MAPT (0.59) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| Cefatrizine SCHEMBL407704 | 0.98 | MAPT (0.58) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| Cefatrizine SCHEMBL9580226 | 0.98 | MAPT (0.60) | MAPTHSD17B10KMT2AMEN1SLC15A2 | |
| Cefatrizine SCHEMBL4645020 | 0.97 | MAPT (0.59) | MAPTHSD17B10KMT2AMEN1SLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4028355-A | Cephalosporin purification process | SMITHKLINE CORPORATION (US) | 1977-06-07 | — | — | US | claimed |
| EP-0011513-B1 | PROCESS FOR PREPARING BETA-LACTAM ANTIBIOTICS | PLANTEX LIMITED (IL) | 1982-09-22 | — | — | EP | disclosed |
| US-4254029-A | SILYLATION, AMIDATION WITH A PHENYLGLYCYL CHLORIDE HYDROCHLORIDE AND HYDROLYSIS TO PRODUCE PENICILLIN AND CEPHALOSPORIN DERIVATIVES | PLANTEX LTD. (IL) | 1981-03-03 | — | — | US | disclosed |
| US-4028355-A | Cephalosporin purification process | SMITHKLINE CORPORATION (US) | 1977-06-07 | — | — | US | disclosed |
| US-3985739-A | 3-Heterocyclic thiomethylcephalosporins | SMITHKLINE CORPORATION (US) | 1976-10-12 | — | — | US | disclosed |