Cefatrizine

Cefatrizine

SCHEMBL49503

N[C@@H](C(=O)N[C@@H]1C(=O)N2C(C(=O)O)=C(CSc3c[nH]nn3)CS[C@H]12)c1ccc(O)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.61
HSD17B10 Q99714 7/20 0.61
KMT2A Q03164 5/20 0.61
MEN1 O00255 4/20 0.61
SLC15A2 Q16348 3/20 0.61
SLC22A6 Q4U2R8 3/20 0.61
SLC22A8 Q8TCC7 3/20 0.61
LMNA P02545 2/20 0.61
ESR1 P03372 1/20 0.61
PTGS1 P23219 1/20 0.58
DRD2 P14416 1/20 0.57
PTGS2 P35354 1/20 0.57
DRD3 P35462 1/20 0.57
ALDH1A1 P00352 7/20 0.56
KDM4E B2RXH2 4/20 0.51
HPGD P15428 3/20 0.51
CYP3A4 P08684 3/20 0.51
TDP1 Q9NUW8 3/20 0.51
CYP2C9 P11712 2/20 0.51
NR1I2 O75469 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cefatrizine SCHEMBL28000091 1.00 MAPT (0.61) MAPTHSD17B10KMT2AMEN1SLC15A2
Cefatrizine SCHEMBL3688526 1.00 MAPT (0.61) MAPTHSD17B10KMT2AMEN1SLC15A2
Cefatrizine SCHEMBL11247780 1.00 MAPT (0.61) MAPTHSD17B10KMT2AMEN1SLC15A2
Cefatrizine SCHEMBL11671021 1.00 MAPT (0.61) MAPTHSD17B10KMT2AMEN1SLC15A2
Cefatrizine SCHEMBL10520664 0.99 MAPT (0.60) MAPTHSD17B10KMT2AMEN1SLC15A2
Cefatrizine SCHEMBL27940222 0.98 MAPT (0.61) MAPTHSD17B10KMT2AMEN1SLC15A2
Cefatrizine SCHEMBL17867569 0.98 MAPT (0.59) MAPTHSD17B10KMT2AMEN1SLC15A2
Cefatrizine SCHEMBL407704 0.98 MAPT (0.58) MAPTHSD17B10KMT2AMEN1SLC15A2
Cefatrizine SCHEMBL9580226 0.98 MAPT (0.60) MAPTHSD17B10KMT2AMEN1SLC15A2
Cefatrizine SCHEMBL4645020 0.97 MAPT (0.59) MAPTHSD17B10KMT2AMEN1SLC15A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8596 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637481-B2 Boronic acid derivatives and therapeutic uses thereof QPEX BIOPHARMA, INC. (US) 2026-05-26 US claimed
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US claimed
US-12576124-B2 Formulation of a conjugate of a tubulysin analog to a cell-binding molecule HANGZHOU DAC BIOTECH CO., LTD (CN) 2026-03-17 US claimed
US-20250339551-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE DIFFERENT FUNCTIONAL SMALL MOLECULES FOR ENHANCED TREATMENT OF REFRACTORY DISEASES HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) 2025-11-06 US claimed
EP-4642484-A1 TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
EP-4642492-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE FUNCTIONAL SMALL MOLECULE COMPOUNDS FOR ENHANCED TREATMENT OF REFRACTORY DISEASES Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
US-12371429-B2 Antibiotic resistance-modifying tricyclic heteroaryl compounds and uses thereof RECREO PHARMACEUTICALS LLC (US) 2025-07-29 US claimed
US-20250222118-A1 Beta-Lactam-Cannabinoid Conjugate Molecules DIVERSE BIOTECH INC (US) 2025-07-10 US claimed
US-12274830-B2 Nitric oxide inhalation therapy for infants with bronchiolitis BEYOND AIR LTD (IL) 2025-04-15 US claimed
US-20250099557-A1 ANTIBIOTIC PHARMACEUTICAL COMPOSITION CAPABLE OF SUBCUTANEOUS ADMINISTRATION SHANGHAI BAO PHARMACEUTICALS CO., LTD. (CN) 2025-03-27 US claimed
US-4452796-A ANTIBIOTICS PFIZER INC. (US) 1984-06-05 US claimed
US-4427678-A 6-Aminomethylpenicillanic acid 1,1-dioxide derivatives as beta-lactamase inhibitors PFIZER INC. (US) 1984-01-24 US claimed
US-4414204-A WITH A MURAMYL-PEPTIDE CIBA-GEIGY CORPORATION (US) 1983-11-08 US claimed
EP-0084925-A1 6-Aminoalkylpenicillanic acid 1,1-dioxides and derivatives as beta-lactamase inhibitors PFIZER INC. (US) 1983-08-03 EP claimed
EP-0007717-B1 CLAVULANIC ACID DERIVATIVES, A PROCESS FOR THEIR PREPARATION, THEIR USE, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM BEECHAM GROUP PLC (GB) 1982-08-11 EP claimed
EP-0050965-A1 Beta-lactamase inhibitory composition Takeda Chemical Industries, Ltd. (JP) 1982-05-05 EP claimed
EP-0019345-A1 Process for the preparation of a (D-alpha-amino-(p-hydroxyphenyl)-acetamido) group containing cephalosporanic acid derivatives GIST-BROCADES N.V. (NL) 1980-11-26 EP claimed
EP-0007717-A1 Clavulanic acid derivatives, a process for their preparation, their use, and pharmaceutical compositions containing them BEECHAM GROUP PLC (GB) 1980-02-06 EP claimed
EP-0001133-A1 Process for the preparation of 6- D-alpha-amino-(p-hydroxyphenyl)-acetamido penicillanic acid GIST-BROCADES N.V. (NL) 1979-03-21 EP claimed
US-4139702-A Process for preparing cephalosporines DOBFAR S.P.A. (IT) 1979-02-13 US claimed