Cefatrizine

Cefatrizine

SCHEMBL9580226

COC.N[C@@H](C(=O)N[C@@H]1C(=O)N2C(C(=O)O)=C(CSc3c[nH]nn3)CS[C@H]12)c1ccc(O)cc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.60
HSD17B10 Q99714 7/20 0.60
KMT2A Q03164 5/20 0.60
MEN1 O00255 4/20 0.60
SLC15A2 Q16348 3/20 0.60
SLC22A6 Q4U2R8 3/20 0.60
SLC22A8 Q8TCC7 3/20 0.60
LMNA P02545 2/20 0.60
ESR1 P03372 1/20 0.60
PTGS1 P23219 1/20 0.58
DRD2 P14416 1/20 0.56
PTGS2 P35354 1/20 0.56
DRD3 P35462 1/20 0.56
ALDH1A1 P00352 7/20 0.56
CYP3A4 P08684 3/20 0.51
HPGD P15428 3/20 0.51
TDP1 Q9NUW8 3/20 0.51
BLM P54132 1/20 0.51
CYP2C19 P33261 1/20 0.51
MAPK1 P28482 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cefatrizine SCHEMBL27940222 0.98 MAPT (0.61) MAPTHSD17B10KMT2AMEN1SLC15A2
Cefatrizine SCHEMBL28000091 0.98 MAPT (0.61) MAPTHSD17B10KMT2AMEN1SLC15A2
Cefatrizine SCHEMBL49503 0.98 MAPT (0.61) MAPTHSD17B10KMT2AMEN1SLC15A2
Cefatrizine SCHEMBL3688526 0.98 MAPT (0.61) MAPTHSD17B10KMT2AMEN1SLC15A2
Cefatrizine SCHEMBL11671021 0.98 MAPT (0.61) MAPTHSD17B10KMT2AMEN1SLC15A2
Cefatrizine SCHEMBL11247780 0.98 MAPT (0.61) MAPTHSD17B10KMT2AMEN1SLC15A2
Cefatrizine SCHEMBL10520664 0.97 MAPT (0.60) MAPTHSD17B10KMT2AMEN1SLC15A2
Cefatrizine SCHEMBL4645020 0.96 MAPT (0.59) MAPTHSD17B10KMT2AMEN1SLC15A2
Cefatrizine SCHEMBL17867569 0.96 MAPT (0.59) MAPTHSD17B10KMT2AMEN1SLC15A2
Cefatrizine SCHEMBL407704 0.96 MAPT (0.58) MAPTHSD17B10KMT2AMEN1SLC15A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5244929-A Catalysts VEBA OEL AKTIENGESELLSCHAFT (DE) 1993-09-14 US disclosed