Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10898673 | 0.89 | MAPT (0.40) | KMT2AMEN1MAPTCYP19A1GAA | |
| SCHEMBL10674513 | 0.88 | KMT2A (0.41) | KMT2AMEN1MAPTCYP19A1TSHR | |
| SCHEMBL10990810 | 0.84 | KMT2A (0.46) | KMT2AMEN1CYP19A1TSHRHSP90AA1 | |
| SCHEMBL10344940 | 0.83 | TSHR (0.39) | KMT2AMEN1TSHRHSD17B10MC4R | |
| Hydrochloric Acid SCHEMBL10900071 | 0.82 | TSHR (0.38) | KMT2AMEN1TSHRHSD17B10MC4R | |
| SCHEMBL10672451 | 0.81 | MEN1 (0.36) | KMT2AMEN1MAPTCYP19A1TSHR | |
| SCHEMBL11265190 | 0.80 | KDM4E (0.39) | KMT2AMEN1MAPTGAATSHR | |
| SCHEMBL10987307 | 0.79 | CYP1A2 (0.38) | KMT2AMEN1MAPT | |
| SCHEMBL10989724 | 0.78 | CYP1A2 (0.43) | KMT2AMEN1MAPTHSP90AA1HDAC1 | |
| SCHEMBL10675265 | 0.77 | TP53 (0.37) | KMT2AMEN1GAATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010163-B1 | N-DIAZOLYLALKYL-CHLOROACETANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1982-01-06 | — | — | EP | disclosed |