SCHEMBL10344940

SCHEMBL10344940

CCc1ccccc1N(Cn1cccn1)C(=O)C(C)Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
LMNA P02545 2/20 0.36
THRB P10828 2/20 0.36
ADRB2 P07550 1/20 0.35
ADRB1 P08588 1/20 0.35
ADRB3 P13945 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HRH3 Q9Y5N1 1/20 0.34
PSEN1 P49768 1/20 0.34
PSEN2 P49810 1/20 0.34
APH1B Q8WW43 1/20 0.34
NCSTN Q92542 1/20 0.34
APH1A Q96BI3 1/20 0.34
PSENEN Q9NZ42 1/20 0.34
MC4R P32245 1/20 0.33
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10900071 0.99 TSHR (0.38) TSHRLMNATHRBADRB2ADRB1
SCHEMBL9511788 0.89 CYP3A4 (0.39) TSHRLMNAHDAC1HDAC6KEAP1
SCHEMBL10900110 0.89 TSHR (0.38) TSHRLMNATHRBADRB2ADRB1
Hydrochloric Acid SCHEMBL10896165 0.88 TSHR (0.37) TSHRLMNATHRBADRB2ADRB1
SCHEMBL10896123 0.85 TSHR (0.40) TSHRLMNAHDAC1HDAC6HRH3
SCHEMBL11248160 0.83 KMT2A (0.41) TSHRHDAC1HDAC6PSEN1PSEN2
SCHEMBL8460980 0.82 TP53 (0.43) TSHRLMNATHRBHDAC1HDAC6
SCHEMBL11265190 0.82 KDM4E (0.39) TSHRLMNAMEN1KMT2AHTT
SCHEMBL10671174 0.81 NPC1 (0.37) TSHRLMNAHDAC1HDAC6HRH3
SCHEMBL10985478 0.80 KEAP1 (0.41) TSHRTHRBHDAC1HDAC6HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0192111-B1 ISO-UREAS, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1990-05-16 EP disclosed
EP-0121129-B1 2,5-DIHYDRO-5-ARYLIMINO-PYRROLES, PROCESS FOR THEIR PRODUCTION AND THEIR USES AS HERBICIDES BASF Aktiengesellschaft (DE) 1989-02-01 EP disclosed
US-4789747-A BROAD LEAF PLANTS, GRASSES, WEEDS BASF AKTIENGESELLSCHAFT (DE) 1988-12-06 US disclosed
US-4761175-A M-anilido-urethanes and herbicides containing these compounds BASF AKTIENGESELLSCHAFT (DE) 1988-08-02 US disclosed
US-4744812-A HALOGENATED DIPHENYL ETHER BASF AKTIENGESELLSCHAFT (DE) 1988-05-17 US disclosed
US-4726837-A Use of 4H-pyrido[2,3-d][1,3]oxazin-4-one derivatives for controlling undesirable plant growth BASF AKTIENGESELLSCHAFT (DE) 1988-02-23 US disclosed
US-4692187-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1987-09-08 US disclosed
US-4632696-A POSTEMERGENCE, PREEMERGENCE APPLICATIONS BASF AKTIENGESELLSCHAFT (DE) 1986-12-30 US disclosed
US-4614537-A PLANT SAFENING AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1986-09-30 US disclosed
EP-0192111-A1 Iso-ureas, processes for their production and their use as herbicides BASF Aktiengesellschaft (DE) 1986-08-27 EP disclosed
EP-0032242-A1 4H-3,1-benzoxazine derivatives, process for their preparation and their use in inhibiting the growth of unwanted plants BASF Aktiengesellschaft (DE) 1981-07-22 EP disclosed
EP-0028355-A1 1,2-Oxazolylalkyl carbamates, their preparation, their use as herbicides, and herbicides BASF Aktiengesellschaft (DE) 1981-05-13 EP disclosed
EP-0024570-A1 5-Imino-imidazoline-2-ones, herbicides containing them and process for destructing undesired plants BASF Aktiengesellschaft (DE) 1981-03-11 EP disclosed
EP-0024669-A1 Substituted N-benzoylanthranilic acid derivatives and their anhydro derivatives, process for their preparation, their use as herbicides and compositions therefor BASF Aktiengesellschaft (DE) 1981-03-11 EP disclosed
EP-0023306-A1 N-(Alpha-chloropropionyl)-1,2,3,4-tetrahydro-quinaldine, process for its preparation and its use as antidote in preventing damage to crops by herbicides BAYER AG (DE) 1981-02-04 EP disclosed
EP-0023308-A1 N-acyl-piperidone cetals, process for their preparation and their use as antidotes in the protection of crop plants against damage by herbicides BAYER AG (DE) 1981-02-04 EP disclosed
EP-0019760-A1 Esters of 3-aryl-5-methyl-pyrazole-4-carboxylic acid, herbicides containing them, process for their preparation and their use BASF Aktiengesellschaft (DE) 1980-12-10 EP disclosed
EP-0018585-A1 Parabanic acid derivatives, herbicides containing them, and process of preparation of these herbicides BASF Aktiengesellschaft (DE) 1980-11-12 EP disclosed
EP-0010159-A1 Agents for selectively combating weeds based on a substituted urea and a halogenacetanilide and their use BAYER AG (DE) 1980-04-30 EP disclosed
EP-0006541-A2 Use of N,N-diallyl-dichloroacetamide for improving the protection of crop plants against herbicidally active acetanilides BAYER AG (DE) 1980-01-09 EP disclosed