SCHEMBL11265190

SCHEMBL11265190

CCc1ccccc1N(Cn1cc(Cl)cn1)C(=O)C(C)Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.39
LMNA P02545 4/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
POLB P06746 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
ALDH1A1 P00352 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
RAB9A P51151 1/20 0.34
ELANE P08246 2/20 0.34
PKM P14618 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
KMT2A Q03164 4/20 0.33
MEN1 O00255 3/20 0.33
HTT P42858 2/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
PLAU P00749 1/20 0.33
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10897351 0.90 LMNA (0.40) KDM4ELMNAHPGDHSD17B10L3MBTL1
SCHEMBL10675265 0.85 TP53 (0.37) KDM4ELMNAHPGDHSD17B10POLB
SCHEMBL10344940 0.82 TSHR (0.39) LMNAHSD17B10L3MBTL1NPSR1KMT2A
Hydrochloric Acid SCHEMBL10900071 0.81 TSHR (0.38) LMNAHSD17B10L3MBTL1NPSR1KMT2A
SCHEMBL11248160 0.80 KMT2A (0.41) HSD17B10KMT2AMEN1GAAMAPT
SCHEMBL10344589 0.78 TRPM8 (0.38) LMNAPOLBALDH1A1NPSR1KMT2A
SCHEMBL10985475 0.72 TAS2R8 (0.39) ALDH1A1PKMHTTGAATSHR
SCHEMBL10897334 0.72 LMNA (0.42) KDM4ELMNAHPGDPOLBALDH1A1
SCHEMBL10900110 0.71 TSHR (0.38) LMNAHPGDKMT2AMEN1HTT
SCHEMBL9511788 0.71 CYP3A4 (0.39) LMNAPOLBALDH1A1ELANENPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4312664-A N,N-DIALLYL-DICHLOROACETAMIDE BAYER AKTIENGESELLSCHAFT (DE) 1982-01-26 US disclosed
EP-0006541-A2 Use of N,N-diallyl-dichloroacetamide for improving the protection of crop plants against herbicidally active acetanilides BAYER AG (DE) 1980-01-09 EP disclosed