Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244850 | 0.94 | HMOX1 (0.84) | HMOX1 | |
| SCHEMBL11250755 | 0.92 | HMOX1 (0.88) | HMOX1 | |
| SCHEMBL11244208 | 0.90 | HMOX1 (0.72) | HMOX1 | |
| SCHEMBL11233524 | 0.89 | HMOX1 (0.70) | HMOX1 | |
| SCHEMBL11248535 | 0.87 | HMOX1 (0.66) | HMOX1 | |
| Bromide SCHEMBL11250602 | 0.86 | HMOX1 (0.65) | HMOX1 | |
| SCHEMBL11245993 | 0.85 | HMOX1 (1.00) | HMOX1 | |
| SCHEMBL10247089 | 0.85 | HMOX1 (1.00) | HMOX1 | |
| SCHEMBL10246975 | 0.85 | HMOX1 (1.00) | HMOX1 | |
| SCHEMBL10247096 | 0.85 | HMOX1 (1.00) | HMOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094095-A2 | Bicyclic carboxylic acids and their alkyl and aralkyl esters | F. HOFFMANN-LA ROCHE AG (CH) | 1983-11-16 | — | — | EP | disclosed |
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |