SCHEMBL11248231

SCHEMBL11248231

CC(=O)[C@@]1(COC(=O)NC(C)C)C[C@@H]2C=C[C@H]1C2

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11071794 1.00 ALDH1A1 (0.31) ALDH1A1CYP3A4TSHRCYP2D6CYP2C19
SCHEMBL11259982 1.00 ALDH1A1 (0.31) ALDH1A1CYP3A4TSHRCYP2D6CYP2C19
SCHEMBL11072263 0.90
SCHEMBL11265898 0.90
SCHEMBL11077377 0.89 HRH3 (0.34) ALDH1A1CYP2D6CYP2C19
SCHEMBL11262825 0.89
SCHEMBL11099867 0.88 HRH3 (0.38)
SCHEMBL11255965 0.88 HRH3 (0.40)
SCHEMBL11247837 0.88 HRH3 (0.39)
SCHEMBL11077970 0.88 HRH3 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4335138-A HYPNOTIC, SEDATIVE BASF AKTIENGESELLSCHAFT (DE) 1982-06-15 US claimed
US-4335138-A HYPNOTIC, SEDATIVE BASF AKTIENGESELLSCHAFT (DE) 1982-06-15 US disclosed
EP-0026369-A2 Carbamates, their preparation and pharmaceutical compositions containing them BASF Aktiengesellschaft (DE) 1981-04-08 EP disclosed