Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11099867 | 0.98 | HRH3 (0.38) | HRH3CA12CA1CA2MMP2 | |
| SCHEMBL11247837 | 0.95 | HRH3 (0.39) | HRH3EPHX2 | |
| SCHEMBL11077970 | 0.95 | HRH3 (0.39) | HRH3EPHX2 | |
| SCHEMBL11248231 | 0.88 | ALDH1A1 (0.31) | — | |
| SCHEMBL11259982 | 0.88 | ALDH1A1 (0.31) | — | |
| SCHEMBL11071794 | 0.88 | ALDH1A1 (0.31) | — | |
| SCHEMBL11109218 | 0.85 | — | — | |
| SCHEMBL11251126 | 0.84 | HRH3 (0.38) | HRH3 | |
| SCHEMBL11265898 | 0.84 | — | — | |
| SCHEMBL11255902 | 0.84 | EPHX1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335138-A | HYPNOTIC, SEDATIVE | BASF AKTIENGESELLSCHAFT (DE) | 1982-06-15 | — | — | US | disclosed |
| EP-0026369-A2 | Carbamates, their preparation and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1981-04-08 | — | — | EP | disclosed |