SCHEMBL11248378

SCHEMBL11248378

C[C@@]1(OC(=O)O)CCCO1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.31
GLS O94925 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6631845 1.00 FFAR3 (0.31) FFAR3GLS
SCHEMBL11246635 1.00 FFAR3 (0.31) FFAR3GLS
SCHEMBL10875348 0.94 FFAR3 (0.30) FFAR3
SCHEMBL28017556 0.85 GLS (0.31) GLS
SCHEMBL6321804 0.79 TSHR (0.37)
SCHEMBL4365632 0.77 TSHR (0.32)
SCHEMBL28610037 0.77
SCHEMBL18338888 0.77
SCHEMBL9544955 0.75
SCHEMBL6430899 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0006449-B1 2-(2-ALKOXYETHYL)-2'-HYDROXY-6.7-BENZOMORPHANE DERIVATIVES, THEIR ACID ADDITION SALTS, MEDICAMENTS CONTAINING THEM AND PROCESS FOR THEIR PREPARATION C.H. BOEHRINGER SOHN (DE) 1982-12-08 EP disclosed
EP-0006449-A1 2-(2-Alkoxyethyl)-2'-hydroxy-6.7-benzomorphane derivatives, their acid addition salts, medicaments containing them and process for their preparation C.H. BOEHRINGER SOHN (DE) 1980-01-09 EP disclosed