⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27552918 | 0.86 | TSHR (0.32) | — | |
| SCHEMBL10875348 | 0.81 | FFAR3 (0.30) | — | |
| SCHEMBL4365632 | 0.80 | TSHR (0.32) | — | |
| SCHEMBL246034 | 0.79 | — | — | |
| SCHEMBL10875212 | 0.78 | NPSR1 (0.32) | — | |
| SCHEMBL10667942 | 0.77 | — | — | |
| SCHEMBL28906906 | 0.76 | TSHR (0.36) | — | |
| SCHEMBL28017556 | 0.76 | GLS (0.31) | — | |
| SCHEMBL11246635 | 0.75 | FFAR3 (0.31) | — | |
| SCHEMBL11248378 | 0.75 | FFAR3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1321140-B1 | IBUPROFEN SOLUTIONS FOR CAPSULE-FILLING AND CAPSULE PREPARATIONS | KOWA CO (JP) | 2005-04-06 | — | — | EP | disclosed |
| US-20030187070-A1 | Ibuprofen solutions for capsule-filling and capsule preparations | KOWA COMPANY, LTD. (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1321140-A1 | IBUPROFEN SOLUTIONS FOR CAPSULE-FILLING AND CAPSULE PREPARTIONS | KOWA COMPANY, LTD. (JP) | 2003-06-25 | — | — | EP | disclosed |