Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | FFAR2 | O15552 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11110226 | 0.93 | ACE (0.53) | KMT2AACEFFAR2POLBGAA | |
| SCHEMBL11234749 | 0.89 | ACE (0.47) | KMT2AACEFFAR2HSD17B10ALDH1A1 | |
| SCHEMBL11068373 | 0.89 | KMT2A (0.50) | KMT2AACEFFAR2POLBGAA | |
| SCHEMBL11474215 | 0.89 | POLB (0.47) | ACEFFAR2POLBGAARAB9A | |
| SCHEMBL11474221 | 0.89 | POLB (0.47) | ACEFFAR2POLBGAARAB9A | |
| SCHEMBL11474211 | 0.89 | POLB (0.47) | ACEFFAR2POLBGAARAB9A | |
| SCHEMBL11184570 | 0.87 | POLB (0.47) | KMT2AFFAR2POLBGAARAB9A | |
| SCHEMBL11092324 | 0.86 | KMT2A (0.40) | KMT2AACEFFAR2POLBGAA | |
| SCHEMBL11065209 | 0.84 | ACE (0.49) | KMT2AACEFFAR2 | |
| SCHEMBL11169739 | 0.84 | ACE (0.49) | KMT2AACEFFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356183-A | ENZYME INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-10-26 | — | — | US | claimed |