Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 3/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11474211 | 1.00 | POLB (0.47) | POLBGAARAB9AACEFFAR2 | |
| SCHEMBL11474215 | 1.00 | POLB (0.47) | POLBGAARAB9AACEFFAR2 | |
| SCHEMBL11184570 | 0.90 | POLB (0.47) | POLBGAARAB9AFFAR2HSD17B10 | |
| SCHEMBL11248462 | 0.89 | KMT2A (0.49) | POLBGAARAB9AACEFFAR2 | |
| SCHEMBL11200469 | 0.84 | POLB (0.48) | POLBGAARAB9AACE | |
| SCHEMBL11244020 | 0.84 | POLB (0.48) | POLBGAARAB9AACE | |
| SCHEMBL11442022 | 0.82 | POLB (0.44) | POLBGAARAB9AACEFFAR2 | |
| SCHEMBL11442031 | 0.82 | POLB (0.44) | POLBGAARAB9AACEFFAR2 | |
| SCHEMBL11442004 | 0.82 | POLB (0.44) | POLBGAARAB9AACEFFAR2 | |
| SCHEMBL11110226 | 0.81 | ACE (0.53) | POLBGAARAB9AACEFFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55000331-A | — | — | None | — | — | JP | disclosed |
| JP-S55331-A | THIAZOLIDINECARBOXYLIC ACID DERIVATIVE AND ITS PREPARATION | YOSHITOMI PHARMACEUT IND LTD | 1980-01-05 | — | — | JP | disclosed |