Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068373 | 0.94 | KMT2A (0.50) | ACEKMT2AHSD17B10FFAR2POLB | |
| SCHEMBL11248462 | 0.93 | KMT2A (0.49) | ACEKMT2AHSD17B10FFAR2POLB | |
| SCHEMBL11234749 | 0.90 | ACE (0.47) | ACEKMT2AHSD17B10FFAR2ALDH1A1 | |
| SCHEMBL11062257 | 0.87 | ACE (0.55) | ACEKMT2AFFAR2 | |
| SCHEMBL11169739 | 0.86 | ACE (0.49) | ACEKMT2AFFAR2 | |
| SCHEMBL11065209 | 0.86 | ACE (0.49) | ACEKMT2AFFAR2 | |
| SCHEMBL11184479 | 0.86 | FFAR2 (0.52) | ACEKMT2AHSD17B10FFAR2POLB | |
| SCHEMBL11066444 | 0.85 | ACE (0.43) | ACEKMT2AHSD17B10FFAR2ALDH1A1 | |
| SCHEMBL11104679 | 0.83 | ACE (0.46) | ACEKMT2AFFAR2 | |
| SCHEMBL11181655 | 0.83 | ACE (0.50) | ACEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4457935-A | ANGIOTENSIN-CONVERTING ENZYME INHIBITOR | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-07-03 | — | — | US | claimed |