Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.40 |
| ▸ | CA9 | Q16790 | 5/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10625365 | 0.88 | APEX1 (0.38) | TSHRSMN1; SMN2ALOX15APEX1CA12 | |
| SCHEMBL11049676 | 0.86 | CA1 (0.40) | SMN1; SMN2APEX1CA12CA9CA1 | |
| SCHEMBL10625337 | 0.86 | TSHR (0.45) | TSHRSMN1; SMN2ALOX15APEX1CA12 | |
| SCHEMBL10944695 | 0.83 | SMN1; SMN2 (0.62) | TSHRSMN1; SMN2ALOX15APEX1CA12 | |
| SCHEMBL23748711 | 0.82 | CA12 (0.51) | TSHRSMN1; SMN2CA12CA9CA2 | |
| SCHEMBL1586444 | 0.78 | ALOX15 (0.49) | TSHRSMN1; SMN2ALOX15CA12CA9 | |
| SCHEMBL9657624 | 0.78 | ALDH1A1 (0.42) | TSHRSMN1; SMN2ALOX15APEX1CA12 | |
| SCHEMBL14100694 | 0.76 | ALOX15 (0.50) | TSHRSMN1; SMN2ALOX15CA12CA9 | |
| SCHEMBL147992 | 0.76 | ALOX15 (0.50) | TSHRSMN1; SMN2ALOX15CA12CA9 | |
| SCHEMBL29843488 | 0.75 | CA1 (0.50) | TSHRALOX15CA12CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045488-A2 | Water-soluble fibre-reactive compounds and their use in finishing textiles, as well as the beta-chloroethyl-sulfonyl-methyl-benzoic-acid halogenides, and their use as a fibre-reactive anchor | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-02-10 | — | — | EP | disclosed |