Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | CASP1 | P29466 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11248603 | 0.83 | MAPT (0.57) | KMT2AMEN1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL11255191 | 0.83 | MEN1 (0.57) | KMT2AMEN1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL5504180 | 0.79 | MEN1 (0.45) | KMT2AMEN1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL2097653 | 0.79 | IDO1 (0.65) | KMT2AMEN1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL21727861 | 0.76 | MEN1 (0.50) | KMT2AMEN1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL10539465 | 0.76 | CYP3A4 (0.63) | KMT2AMEN1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL11344109 | 0.75 | IDO1 (0.47) | KMT2AMEN1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL10764611 | 0.75 | MEN1 (0.61) | KMT2AMEN1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL51173 | 0.75 | CYP3A4 (0.67) | KMT2AMEN1CYP3A4MAPTSMN1; SMN2 | |
| SCHEMBL8053473 | 0.74 | CYP2C9 (0.69) | KMT2AMEN1CYP3A4MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336270-A | BACTERICIDES, FUNGICIDES | CIBA-GEIGY CORPORATION (US) | 1982-06-22 | — | — | US | claimed |