Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | RECQL | P46063 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2436211 | 0.90 | ALDH1A1 (0.79) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL30159613 | 0.90 | ALDH1A1 (0.79) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL29151237 | 0.89 | ALDH1A1 (0.72) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL10507211 | 0.89 | ALDH1A1 (0.77) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL10507215 | 0.89 | ALDH1A1 (0.77) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL8973886 | 0.83 | ALDH1A1 (0.58) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL10507447 | 0.83 | ALDH1A1 (0.68) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL14601545 | 0.82 | ALDH1A1 (0.63) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL5678530 | 0.81 | ALDH1A1 (0.61) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL10016575 | 0.80 | MAPT (1.00) | ALDH1A1LMNAKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4346242-A | Method for preparing substituted meta-phenylalkoxynitrobenzenes | AMERICAN CYANAMID COMPANY (US) | 1982-08-24 | — | — | US | disclosed |