Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5678530 | 0.92 | ALDH1A1 (0.61) | ALDH1A1LMNAKMT2AMEN1RECQL | |
| SCHEMBL5678528 | 0.90 | ALDH1A1 (0.59) | ALDH1A1LMNAKMT2AMEN1RECQL | |
| SCHEMBL11052582 | 0.89 | ALDH1A1 (0.57) | ALDH1A1LMNAKMT2AMEN1RECQL | |
| SCHEMBL845821 | 0.89 | ALDH1A1 (0.58) | ALDH1A1LMNAKMT2AMEN1RECQL | |
| SCHEMBL845822 | 0.89 | ALDH1A1 (0.58) | ALDH1A1LMNAKMT2AMEN1RECQL | |
| SCHEMBL30159613 | 0.87 | ALDH1A1 (0.79) | ALDH1A1LMNAKMT2AMEN1RECQL | |
| SCHEMBL2436211 | 0.87 | ALDH1A1 (0.79) | ALDH1A1LMNAKMT2AMEN1RECQL | |
| SCHEMBL10507211 | 0.86 | ALDH1A1 (0.77) | ALDH1A1LMNAKMT2AMEN1RECQL | |
| SCHEMBL10507215 | 0.86 | ALDH1A1 (0.77) | ALDH1A1LMNAKMT2AMEN1RECQL | |
| SCHEMBL6063920 | 0.84 | ALDH1A1 (0.53) | ALDH1A1LMNAKMT2AMEN1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7161022-B2 | Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |
| US-7161022-B2 | Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative | FUJIFILM FINECHEMICALS CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |