Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 14/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246732 | 0.83 | PTGDR2 (0.52) | PTGDR2LMNAPOLBALDH1A1MAPT | |
| SCHEMBL11249311 | 0.82 | RPA1 (0.51) | CA1CA2PTGDR2LMNAPOLB | |
| SCHEMBL11249550 | 0.82 | CA1 (0.58) | CA1CA2PTGDR2 | |
| Trifezolac SCHEMBL11182574 | 0.78 | KDM4E (0.51) | CA1CA2PTGDR2LMNAALDH1A1 | |
| SCHEMBL11242908 | 0.78 | PTGDR2 (0.50) | PTGDR2 | |
| SCHEMBL11250252 | 0.78 | CNR1 (0.51) | PTGDR2 | |
| SCHEMBL11255798 | 0.76 | MARS1 (0.50) | PTGDR2 | |
| SCHEMBL11245710 | 0.75 | PTGDR2 (0.51) | PTGDR2POLBALDH1A1KDM4E | |
| SCHEMBL11254556 | 0.73 | PTGDR2 (0.47) | PTGDR2ALDH1A1KMT2AKDM4E | |
| SCHEMBL11254211 | 0.73 | CA1 (0.53) | CA1CA2PTGDR2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325962-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |