Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.50 |
| ▸ | CNR1 | P21554 | 11/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250252 | 0.89 | CNR1 (0.51) | PTGDR2CNR1AKR1B1 | |
| SCHEMBL11255798 | 0.80 | MARS1 (0.50) | PTGDR2CNR1 | |
| SCHEMBL11248645 | 0.78 | CA1 (0.52) | PTGDR2 | |
| SCHEMBL11254556 | 0.77 | PTGDR2 (0.47) | PTGDR2CNR1 | |
| Trifezolac SCHEMBL11182574 | 0.77 | KDM4E (0.51) | PTGDR2 | |
| SCHEMBL11255212 | 0.77 | PTGDR2 (0.54) | PTGDR2 | |
| SCHEMBL11246732 | 0.77 | PTGDR2 (0.52) | PTGDR2 | |
| SCHEMBL11261876 | 0.76 | KDM4E (0.54) | PTGDR2 | |
| SCHEMBL11249311 | 0.76 | RPA1 (0.51) | PTGDR2 | |
| SCHEMBL11699362 | 0.76 | KDM4E (0.55) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325962-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |