Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | RAD52 | P43351 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21033413 | 0.86 | MAPT (0.64) | ALDH1A1KDM4ESMN1; SMN2MAPTHPGD | |
| SCHEMBL5673533 | 0.86 | ALDH1A1 (0.63) | ALDH1A1KDM4ESMN1; SMN2MAPTHPGD | |
| SCHEMBL2017818 | 0.85 | KDM4E (0.82) | ALDH1A1KDM4ESMN1; SMN2MAPTHPGD | |
| SCHEMBL11241812 | 0.85 | MAPT (0.63) | ALDH1A1KDM4ESMN1; SMN2MAPTHPGD | |
| Phosphoric Acid SCHEMBL11249952 | 0.82 | KDM4E (0.76) | ALDH1A1KDM4ESMN1; SMN2MAPTHPGD | |
| Hydrochloric Acid SCHEMBL11242122 | 0.81 | MAPT (0.75) | ALDH1A1KDM4ESMN1; SMN2MAPTHPGD | |
| SCHEMBL11248352 | 0.81 | SMN1; SMN2 (0.52) | ALDH1A1KDM4ESMN1; SMN2MAPTHPGD | |
| SCHEMBL7009190 | 0.80 | KMT2A (0.67) | ALDH1A1KDM4ESMN1; SMN2MAPTHPGD | |
| Hydrochloric Acid SCHEMBL11241074 | 0.80 | MAPT (0.56) | ALDH1A1KDM4ESMN1; SMN2MAPTHPGD | |
| Hydrochloric Acid SCHEMBL11241070 | 0.80 | MAPT (0.56) | ALDH1A1KDM4ESMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343804-A | 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds | A. H. ROBINS COMPANY, INC. (US) | 1982-08-10 | — | — | US | disclosed |