Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.52 |
| ▸ | RELA | Q04206 | 2/20 | 0.52 |
| ▸ | CCR6 | P51684 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | STAT1 | P42224 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7009190 | 0.87 | KMT2A (0.67) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL17128232 | 0.87 | ELANE (0.46) | NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL6556908 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL21101257 | 0.85 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL11249360 | 0.83 | MAPT (0.57) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL6200113 | 0.83 | CCR6 (0.54) | NPC1RAB9AMAPTCCR6ALDH1A1 | |
| SCHEMBL11704307 | 0.83 | HNF4A (0.45) | SMN1; SMN2NPC1RAB9AMAPTALDH1A1 | |
| SCHEMBL11241812 | 0.83 | MAPT (0.63) | SMN1; SMN2MAPTALDH1A1MAPK1TP53 | |
| SCHEMBL9814048 | 0.82 | KMT2A (0.51) | NPC1RAB9AMAPTALDH1A1LMNA | |
| SCHEMBL11248734 | 0.81 | ALDH1A1 (0.62) | SMN1; SMN2RAB9AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343804-A | 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds | A. H. ROBINS COMPANY, INC. (US) | 1982-08-10 | — | — | US | disclosed |