SCHEMBL11248768

SCHEMBL11248768

CC1(C)C2CCC1(C)C(O)(Cc1ccc(Cl)cc1)C2

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.40
CXCR3 P49682 1/20 0.39
TRPA1 O75762 1/20 0.36
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
GAA P10253 1/20 0.35
P2RX7 Q99572 1/20 0.34
SLC6A1 P30531 1/20 0.34
SLC6A12 P48065 1/20 0.34
SLC6A11 P48066 1/20 0.34
POLB P06746 1/20 0.34
SSTR1 P30872 1/20 0.34
SSTR4 P31391 1/20 0.34
DRD2 P14416 2/20 0.33
DRD4 P21917 2/20 0.33
DRD3 P35462 1/20 0.33
FPR2 P25090 1/20 0.33
PROKR1 Q8TCW9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11251634 0.85 SLC6A1 (0.43) LMNACXCR3TRPA1SLC6A1SLC6A12
SCHEMBL11254143 0.75 LMNA (0.42) LMNAMEN1ALDH1A1KMT2ASMN1; SMN2
SCHEMBL11262967 0.71 SLC6A1 (0.53) LMNACXCR3GAAP2RX7SLC6A1
SCHEMBL9823374 0.71 SLC6A1 (0.33) SLC6A1SLC6A12SLC6A11
SCHEMBL8133320 0.71 SLC6A1 (0.33) SLC6A1SLC6A12SLC6A11
SCHEMBL9823369 0.71 SLC6A1 (0.33) SLC6A1SLC6A12SLC6A11
SCHEMBL11251560 0.70 SLC6A1 (0.46) LMNACXCR3GAASLC6A1SLC6A12
SCHEMBL27580411 0.69 PLA2G1B (0.34) LMNAKMT2ASMN1; SMN2SLC6A1SLC6A12
SCHEMBL8755099 0.68 SLC6A1 (0.31) SLC6A1SLC6A12SLC6A11
SCHEMBL4612981 0.68 SLC6A1 (0.31) SLC6A1SLC6A12SLC6A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4342762-A USEFUL AS TRANQUILIZERS, ANALGESICS, ANTIEPILEPTIC AGENTS, AND AS A TREATMENT FOR PARKINSON'S DISEASE EGYT GYOGYSZERVEGYESZETI GYAR (HU) 1982-08-03 US disclosed