SCHEMBL112488

SCHEMBL112488

COC(=O)Cc1ccc(O)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.66
CYP4A11 Q02928 1/20 0.66
HSP90AB1 P08238 1/20 0.64
ALDH1A1 P00352 3/20 0.58
GAA P10253 2/20 0.58
GFER P55789 1/20 0.58
CA2 P00918 3/20 0.56
CAMK2A Q9UQM7 1/20 0.56
SENP1 Q9P0U3 1/20 0.51
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
HTT P42858 1/20 0.50
FNTA P49354 1/20 0.50
FNTB P49356 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
LMNA P02545 2/20 0.49
MAPT P10636 1/20 0.49
TP53 P04637 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
ESR1 P03372 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7646563 0.98 CYP4F2 (0.63) CYP4F2CYP4A11HSP90AB1ALDH1A1GAA
Hydrochloric Acid SCHEMBL27517466 0.98 CYP4F2 (0.63) CYP4F2CYP4A11HSP90AB1ALDH1A1GAA
SCHEMBL4113212 0.91 CYP4F2 (0.76) CYP4F2CYP4A11HSP90AB1ALDH1A1GAA
SCHEMBL27661252 0.91 CYP4F2 (0.56) CYP4F2CYP4A11HSP90AB1ALDH1A1GAA
SCHEMBL15522740 0.91 CYP4F2 (0.66) CYP4F2CYP4A11HSP90AB1ALDH1A1GAA
SCHEMBL6934357 0.89 CYP4F2 (0.54) CYP4F2CYP4A11HSP90AB1ALDH1A1GAA
SCHEMBL12256030 0.87 HSP90AB1 (0.55) CYP4F2CYP4A11HSP90AB1ALDH1A1GAA
SCHEMBL5802908 0.86 CA2 (0.50) CYP4F2CYP4A11HSP90AB1ALDH1A1GAA
SCHEMBL28344886 0.83 CYP4F2 (0.49) CYP4F2CYP4A11HSP90AB1ALDH1A1GAA
SCHEMBL29789029 0.83 PTGS2 (0.53) CYP4F2CYP4A11HSP90AB1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2246 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116041004-B Super-early-strength concrete and preparation method thereof 江苏建苑建筑材料研究所有限责任公司 2024-05-28 CN claimed
CN-117384136-A NO donor type antifungal compound and preparation method and application thereof 中国药科大学 2024-01-12 CN claimed
US-20230345936-A1 NOVEL ENVIRONMENT-FRIENDLY HERBICIDE KUNMING INSTITUTE OF BOTANY, CHINESE ACADEMY OF SCIENCES (CN) 2023-11-02 US claimed
CN-114903043-B Application of novel green pesticide 中国科学院昆明植物研究所 2023-07-28 CN claimed
CN-116041004-A Super-early-strength concrete and preparation method thereof 江苏建苑建筑材料研究所有限责任公司 2023-05-02 CN claimed
CN-114903043-A Application of novel green pesticide 中国科学院昆明植物研究所 2022-08-16 CN claimed
CN-114436905-A Purification method of 3-aldehyde-4-hydroxy methyl phenylacetate 攀枝花学院 2022-05-06 CN claimed
CN-111362841-B Method for para-amination dearomatization of phenol compound 武汉英纳氏药业有限公司 2022-05-03 CN claimed
CN-108931885-B Low-temperature-cured photosensitive resin composition and application thereof 台湾永光化学工业股份有限公司 2021-08-13 CN claimed
CN-108929396-B Rare earth metal catalyst system and method for preparing high cis conjugated diene polymer 北京化工大学 2020-07-28 CN claimed
CN-102399145-A Method for preparing latamoxef 7-side chain of 1-oxacephems antibiotic TAICANG YUNTONG CHEMICAL FACTORY 2012-04-04 CN claimed
EP-2181989-A2 Process for the preparation of olopatadine Sumitomo Chemical Company, Limited (JP) 2010-05-05 EP claimed
CN-101516865-A Tertiary alkyl ester of oxodibenzoxepin acetic acid SUMITOMO CHEMICAL CO (JP) 2009-08-26 CN claimed
CN-101506141-A Methyl 2- (4-methoxycarbonylmethylphenoxymethyl) benzoate and process for producing the same SUMITOMO CHEMICAL CO (JP) 2009-08-12 CN claimed
EP-2072507-A1 TERTIARY ALKYL ESTER OF OXODIBENZOXEPIN ACETIC ACID Sumitomo Chemical Company, Limited (JP) 2009-06-24 EP claimed
EP-2058294-A1 2-(4-METHOXYCARBONYLMETHYLPHENOXYMETHYL)BENZOIC ACID METHYL ESTER AND METHOD FOR PRODUCING THE SAME Sumitomo Chemical Company, Limited (JP) 2009-05-13 EP claimed
CN-101293868-A Process for synthesizing D-alpha-(6-methyl-4-hydroxyl nicotinamide base)p-hydroxyphenylacetic acid QILU ANTIBIOTICS PHARMACEUTICA (CN) 2008-10-29 CN claimed
EP-0000932-B1 PRODUCTION OF N-ACYL-THIENAMYCINS MERCK & CO. INC. (US) 1981-10-21 EP claimed
EP-0000932-A1 Production of N-acyl-thienamycins MERCK & CO. INC. (US) 1979-03-07 EP claimed
US-4135978-A PRODUCTION OF N-ACYL-THIENAMYCINS MERCK & CO., INC. (US) 1979-01-23 US claimed