Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11248902 | 0.88 | MEN1 (0.46) | ACSS2LMNAEGLN1NPC1RAB9A | |
| SCHEMBL11410279 | 0.79 | ACSS2 (0.55) | ACSS2LMNAEGLN1NPC1RAB9A | |
| SCHEMBL17212254 | 0.75 | ACSS2 (0.64) | ACSS2NPC1RAB9ANPBWR1ALDH1A1 | |
| SCHEMBL18675004 | 0.74 | ACSS2 (1.00) | ACSS2 | |
| SCHEMBL760729 | 0.73 | SMN1; SMN2 (0.57) | LMNANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL3753401 | 0.70 | KDM4E (0.60) | ACSS2LMNAAKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL29281088 | 0.69 | TDP1 (0.45) | ACSS2NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL13844367 | 0.69 | KDM4E (0.59) | ACSS2LMNANPC1RAB9ANPBWR1 | |
| SCHEMBL20457044 | 0.68 | ACSS2 (0.71) | ACSS2 | |
| SCHEMBL11266333 | 0.67 | SMN1; SMN2 (0.51) | LMNANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309551-A | Quaternized, bridged benzimidazolylbenzimidazoles, processes for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-01-05 | — | — | US | disclosed |