Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11248905 | 0.88 | ACSS2 (0.59) | ACSS2CA1ALDH1A1LMNAAKR1C3 | |
| SCHEMBL11558680 | 0.78 | CA12 (0.52) | MEN1KMT2AACSS2CA12CA9 | |
| SCHEMBL11266333 | 0.76 | SMN1; SMN2 (0.51) | MEN1KMT2ARECQLLMNANPC1 | |
| SCHEMBL11488766 | 0.73 | MEN1 (0.49) | MEN1KMT2ARECQLCA12CA9 | |
| SCHEMBL10238322 | 0.73 | ACSS2 (0.52) | ACSS2CA12CA9CA1CA2 | |
| SCHEMBL2364886 | 0.73 | PKM (0.44) | MEN1KMT2APKMLMNACYP2D6 | |
| SCHEMBL3753401 | 0.73 | KDM4E (0.60) | ACSS2ALDH1A1LMNAAKR1C3AKR1C2 | |
| SCHEMBL760729 | 0.73 | SMN1; SMN2 (0.57) | RECQLALDH1A1LMNAGAANPC1 | |
| SCHEMBL11265258 | 0.72 | ALDH1A1 (0.55) | MEN1KMT2ARECQLALDH1A1LMNA | |
| SCHEMBL11557258 | 0.72 | ALDH1A1 (0.55) | MEN1KMT2ARECQLCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309551-A | Quaternized, bridged benzimidazolylbenzimidazoles, processes for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-01-05 | — | — | US | disclosed |
| EP-0027897-A1 | Bridged quaternary benzimidazolyl-benzimidazole derivatives, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-05-06 | — | — | EP | disclosed |