Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 6/20 | 0.75 |
| ▸ | POLB | P06746 | 2/20 | 0.75 |
| ▸ | THRB | P10828 | 1/20 | 0.75 |
| ▸ | F2 | P00734 | 2/20 | 0.66 |
| ▸ | F10 | P00742 | 2/20 | 0.66 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.66 |
| ▸ | F7 | P08709 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.55 |
| ▸ | APAF1 | O14727 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244650 | 0.88 | F2 (0.63) | L3MBTL1MAPTPOLBTHRBF2 | |
| SCHEMBL3410940 | 0.84 | MAPT (0.65) | L3MBTL1MAPTPOLBTHRBF2 | |
| SCHEMBL1064897 | 0.83 | NR1H4 (0.67) | L3MBTL1MAPTPOLBTHRBALDH1A1 | |
| SCHEMBL8462063 | 0.81 | NR1H4 (0.55) | L3MBTL1MAPTPOLBTHRBF2 | |
| SCHEMBL11253068 | 0.81 | MAPT (0.65) | L3MBTL1MAPTPOLBF2F10 | |
| SCHEMBL3612256 | 0.79 | TSHR (0.87) | L3MBTL1POLBTSHRTP53CA1 | |
| SCHEMBL11266561 | 0.78 | MAPT (0.63) | MAPTPOLBTHRBALDH1A1KDM4E | |
| SCHEMBL3412563 | 0.78 | MAPT (0.66) | L3MBTL1MAPTPOLBF2F10 | |
| SCHEMBL7820479 | 0.76 | FFAR1 (0.69) | L3MBTL1MAPTPOLBALDH1A1KDM4E | |
| SCHEMBL8686297 | 0.75 | L3MBTL1 (0.55) | L3MBTL1POLBALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362892-A | ARALKYLANILINES, ANTICHOLESTEROL AGENTS | BEECHAM GROUP LIMITED (GB) | 1982-12-07 | — | — | US | disclosed |
| US-4206145-A | ALKANOYL-SUBSTITUTED ARALKYLAMINES | BEECHAM GROUP LIMITED (GB) | 1980-06-03 | — | — | US | disclosed |