Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | VNN1 | O95497 | 3/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | TPMT | P51580 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8682662 | 0.89 | ALDH1A1 (0.55) | ALDH1A1VNN1GAAKDM4EACHE | |
| SCHEMBL8686290 | 0.85 | ALDH1A1 (0.54) | ALDH1A1GAAKDM4EACHEAPP | |
| SCHEMBL27561188 | 0.78 | HDAC3 (0.52) | VNN1GAA | |
| SCHEMBL8686302 | 0.78 | MAPK8 (0.57) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL11248949 | 0.75 | L3MBTL1 (0.76) | L3MBTL1ALDH1A1NR1H4GAAKDM4E | |
| SCHEMBL1064897 | 0.75 | NR1H4 (0.67) | L3MBTL1ALDH1A1NR1H4GAAKDM4E | |
| SCHEMBL9017142 | 0.74 | ALDH1A1 (0.47) | ALDH1A1GAAKDM4EACHEAPP | |
| SCHEMBL27426334 | 0.74 | MRGPRX4 (0.56) | NR1H4KDM4ECA12CA1CA2 | |
| SCHEMBL4727807 | 0.74 | SMN1; SMN2 (0.74) | L3MBTL1ALDH1A1NR1H4ACHEMEN1 | |
| Water SCHEMBL8681365 | 0.73 | ALDH1A1 (0.46) | ALDH1A1GAAKDM4EACHEAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719187-A | Compounds having a guanidine structure and pharmaceutical composition containing same | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE(CNRS) (FR) | 1998-02-17 | — | — | US | disclosed |
| EP-0572635-B1 | COMPOUNDS HAVING A GUANIDINE STRUCTURE AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | CENTRE NAT RECH SCIENT (FR) | 1996-12-27 | — | — | EP | disclosed |
| US-5480884-A | Compounds having a guanidine structure | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1996-01-02 | — | — | US | disclosed |
| EP-0572635-A1 | NOVEL COMPOUNDS HAVING A GUANIDINE STRUCTURE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME. | CENTRE NAT RECH SCIENT (FR) | 1993-12-08 | — | — | EP | disclosed |
| EP-0572635-A4 | NOVEL COMPOUNDS HAVING A GUANIDINE STRUCTURE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME. | CENTRE NAT RECH SCIENT (FR) | 1993-09-17 | — | — | EP | disclosed |
| WO-1993010102-A1 | NOVEL COMPOUNDS HAVING A GUANIDINE STRUCTURE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) | 1993-05-27 | — | — | WO | disclosed |