Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.72 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.72 |
| ▸ | AR | P10275 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | GUSB | P08236 | 2/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11248956 | 1.00 | MAOB (0.72) | MAOBADORA3ARKDM4ECYP19A1 | |
| Flavanone SCHEMBL19745 | 0.85 | MAOB (1.00) | MAOBADORA3ARKDM4ECYP19A1 | |
| Flavanone SCHEMBL12660199 | 0.85 | MAOB (1.00) | MAOBADORA3ARKDM4ECYP19A1 | |
| Flavanone SCHEMBL12189591 | 0.85 | MAOB (1.00) | MAOBADORA3ARKDM4ECYP19A1 | |
| Flavanone SCHEMBL29470801 | 0.85 | MAOB (1.00) | MAOBADORA3ARKDM4ECYP19A1 | |
| Flavanone SCHEMBL29843289 | 0.85 | MAOB (1.00) | MAOBADORA3ARKDM4ECYP19A1 | |
| SCHEMBL12251332 | 0.84 | AR (0.64) | MAOBADORA3ARKDM4ECYP19A1 | |
| SCHEMBL1890730 | 0.84 | MAOB (1.00) | MAOBADORA3ARKDM4ECYP19A1 | |
| SCHEMBL1890733 | 0.84 | MAOB (1.00) | MAOBADORA3ARKDM4ECYP19A1 | |
| Flavanone SCHEMBL11733114 | 0.83 | MAOB (0.96) | MAOBADORA3ARKDM4ECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025161-B1 | 3-METHYLENE FLAVANONES AND 3-METHYLENE CHROMANONES, ANTIMICROBIAL COMPOSITION CONTAINING SAME AND METHOD OF INHIBITING THE GROWTH OF MICROORGANISMS | MILES LABORATORIES, INC. (US) | 1982-06-09 | — | — | EP | disclosed |
| EP-0025161-A1 | 3-Methylene flavanones and 3-methylene chromanones, antimicrobial composition containing same and method of inhibiting the growth of microorganisms | MILES LABORATORIES, INC. (US) | 1981-03-18 | — | — | EP | disclosed |
| US-4241069-A | MICROBIOCIDES | MILES LABORATORIES, INC. (US) | 1980-12-23 | — | — | US | disclosed |