Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 16/20 | 1.00 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.79 |
| ▸ | AR | P10275 | 1/20 | 0.79 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.79 |
| ▸ | NPC1 | O15118 | 3/20 | 0.73 |
| ▸ | RAB9A | P51151 | 3/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1890733 | 1.00 | MAOB (1.00) | MAOBADORA3KDM4EARCYP19A1 | |
| Flavanone SCHEMBL29470801 | 0.89 | MAOB (1.00) | MAOBADORA3KDM4EARCYP19A1 | |
| Flavanone SCHEMBL29843289 | 0.89 | MAOB (1.00) | MAOBADORA3KDM4EARCYP19A1 | |
| Flavanone SCHEMBL12660199 | 0.89 | MAOB (1.00) | MAOBADORA3KDM4EARCYP19A1 | |
| Flavanone SCHEMBL12189591 | 0.89 | MAOB (1.00) | MAOBADORA3KDM4EARCYP19A1 | |
| Flavanone SCHEMBL19745 | 0.89 | MAOB (1.00) | MAOBADORA3KDM4EARCYP19A1 | |
| Flavanone SCHEMBL27610362 | 0.87 | MAOB (0.90) | MAOBADORA3KDM4EARCYP19A1 | |
| Flavanone SCHEMBL22715765 | 0.87 | MAOB (0.96) | MAOBADORA3KDM4EARCYP19A1 | |
| Flavanone SCHEMBL27281921 | 0.87 | MAOB (0.96) | MAOBADORA3KDM4EARCYP19A1 | |
| Flavanone SCHEMBL11733114 | 0.87 | MAOB (0.96) | MAOBADORA3KDM4EARCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110117649-A1 | Catalytic enantioselective synthesis of flavanones and chromanones | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-05-19 | — | — | US | disclosed |
| US-20110117649-A1 | Catalytic enantioselective synthesis of flavanones and chromanones | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-05-19 | — | — | US | disclosed |
| US-7851640-B2 | Catalytic enantioselective synthesis of flavanones and chromanones | NORTHWESTERN UNIVERSITY (US) | 2010-12-14 | — | — | US | disclosed |
| US-7851640-B2 | Catalytic enantioselective synthesis of flavanones and chromanones | NORTHWESTERN UNIVERSITY (US) | 2010-12-14 | — | — | US | disclosed |
| US-20090259055-A1 | Catalytic enantioselective synthesis of flavanones and chromanones | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-10-15 | — | — | US | disclosed |
| US-20090259055-A1 | Catalytic enantioselective synthesis of flavanones and chromanones | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-10-15 | — | — | US | disclosed |
| US-4461907-A | Amino-substituted flavans useful as anti-viral agents | BURROUGHS WELLCOME CO. | 1984-07-24 | — | — | US | disclosed |
| EP-0004579-B1 | FLAVANS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-08-18 | — | — | EP | disclosed |
| EP-0025161-B1 | 3-METHYLENE FLAVANONES AND 3-METHYLENE CHROMANONES, ANTIMICROBIAL COMPOSITION CONTAINING SAME AND METHOD OF INHIBITING THE GROWTH OF MICROORGANISMS | MILES LABORATORIES, INC. (US) | 1982-06-09 | — | — | EP | disclosed |
| EP-0051061-A2 | Novel intermediates and process for their preparation | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-05-05 | — | — | EP | disclosed |
| EP-0025161-A1 | 3-Methylene flavanones and 3-methylene chromanones, antimicrobial composition containing same and method of inhibiting the growth of microorganisms | MILES LABORATORIES, INC. (US) | 1981-03-18 | — | — | EP | disclosed |
| US-4241069-A | MICROBIOCIDES | MILES LABORATORIES, INC. (US) | 1980-12-23 | — | — | US | disclosed |
| EP-0004579-A1 | Flavans, process for their preparation and pharmaceutical compositions containing them | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-10-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090259055-A1 | Catalytic enantioselective synthesis of flavanones and chromanones | RNGTT, CDK20, TBXAS1 | MAOB 458/4885ADORA3 1130/4885KDM4E 1170/4885 |
| US-20110117649-A1 | Catalytic enantioselective synthesis of flavanones and chromanones | RNGTT, CDK20, TBXAS1 | MAOB 458/4885ADORA3 1130/4885KDM4E 1170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.