Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003650 | 0.85 | NAMPT (0.55) | KMT2AMEN1TACR1HDAC1HDAC6 | |
| SCHEMBL29845593 | 0.84 | KMT2A (0.49) | KMT2AMEN1TACR1HDAC1HDAC6 | |
| SCHEMBL30644814 | 0.84 | KMT2A (0.49) | KMT2AMEN1TACR1HDAC1HDAC6 | |
| SCHEMBL6499535 | 0.79 | HDAC1 (0.47) | KMT2AMEN1TACR1HDAC1HDAC6 | |
| SCHEMBL16941093 | 0.79 | NAMPT (0.56) | KMT2AMEN1HDAC1HDAC6NPC1 | |
| SCHEMBL2321624 | 0.78 | KMT2A (0.44) | KMT2AMEN1TACR1HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL6499537 | 0.78 | HDAC1 (0.46) | KMT2AMEN1TACR1HDAC1HDAC6 | |
| SCHEMBL4585832 | 0.77 | KMT2A (0.53) | KMT2AMEN1HDAC1HDAC6ALDH1A1 | |
| SCHEMBL14461628 | 0.77 | MEN1 (0.43) | KMT2AMEN1TACR1HDAC1HDAC6 | |
| SCHEMBL496380 | 0.77 | CSNK1E (0.47) | KMT2AMEN1HDAC1HDAC6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341893-A | HYPOTENSIVE AGENTS | SYNTHELABO (FR) | 1982-07-27 | — | — | US | disclosed |