SCHEMBL4585832

SCHEMBL4585832

CN(CN)C(=O)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.53
MEN1 O00255 1/20 0.53
HDAC1 Q13547 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
MAOA P21397 1/20 0.49
ADRA2C P18825 1/20 0.47
ALDH1A1 P00352 1/20 0.47
HPGD P15428 1/20 0.47
HSD11B1 P28845 1/20 0.47
F2 P00734 1/20 0.46
ACHE P22303 1/20 0.46
CDK4 P11802 1/20 0.45
CCND1 P24385 1/20 0.45
DPP4 P27487 1/20 0.44
PREP P48147 1/20 0.44
FAP Q12884 1/20 0.44
MLYCD O95822 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1003843 0.84 ADRA2C (0.53) KMT2AMEN1HDAC1HDAC6ADRA2C
SCHEMBL11210779 0.83 KMT2A (0.56) KMT2AMEN1HDAC1HDAC6ALDH1A1
SCHEMBL11248980 0.81 ADRA2C (0.63) KMT2AMEN1HDAC1HDAC6ADRA2C
SCHEMBL1003249 0.81 ALDH1A1 (0.58) KMT2AMEN1HDAC1HDAC6ALDH1A1
SCHEMBL3362719 0.81 KMT2A (0.55) KMT2AMEN1HDAC1HDAC6ALDH1A1
SCHEMBL9873675 0.80 MLYCD (0.53) KMT2AMEN1HDAC1HDAC6ADRA2C
SCHEMBL13906176 0.80 KMT2A (0.50) KMT2AMEN1HDAC1HDAC6MAOA
SCHEMBL17629660 0.79 KMT2A (0.53) KMT2AMEN1HDAC1HDAC6ALDH1A1
SCHEMBL2282162 0.79 KMT2A (0.53) KMT2AMEN1HDAC1HDAC6ALDH1A1
SCHEMBL294286 0.79 KMT2A (0.53) KMT2AMEN1HDAC1HDAC6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230386861-A1 SEMICONDUCTOR DEVICES AND METHODS OF MANUFACTURE TAIWAN SEMICONDUCTOR MFG CO LTD (TW) 2023-11-30 US disclosed
EP-3438113-B1 TETRADENTATE LIGAND, AND PRODUCTION METHOD THEREFOR, SYNTHETIC INTERMEDIATE THEREOF, AND TRANSITION METAL COMPLEX THEREOF TAKASAGO PERFUMERY CO LTD (JP) 2021-02-17 EP disclosed
EP-3438113-A1 TETRADENTATE LIGAND, AND PRODUCTION METHOD THEREFOR, SYNTHETIC INTERMEDIATE THEREOF, AND TRANSITION METAL COMPLEX THEREOF Takasago International Corporation (JP) 2019-02-06 EP disclosed
EP-1537230-A4 FLUORESCENT ENZYME ASSAY METHODS AND COMPOSITIONS APPLERA CORP (US) 2008-06-18 EP disclosed
EP-1537230-A1 FLUORESCENT ENZYME ASSAY METHODS AND COMPOSITIONS Applera Corporation (US) 2005-06-08 EP disclosed
US-20040146959-A1 Fluorescent enzyme assay methods and compositions APPLIED BIOSYSTEMS, LLC 2004-07-29 US disclosed
WO-2004022773-A1 FLUORESCENT ENZYME ASSAY METHODS AND COMPOSITIONS APPLERA CORPORATION (US) 2004-03-18 WO disclosed
US-5736568-A ANTIALLERGENS; IMMUNOMODULANTS KNOLL AKTIENGESELLSCHAFT (DE) 1998-04-07 US disclosed