Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | SDHB | P21912 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11257627 | 0.93 | SOS1 (0.37) | NOTUMSOS1CFTRKDM4EALDH1A1 | |
| SCHEMBL11253288 | 0.92 | SOS1 (0.36) | NOTUMSOS1CFTRKDM4EALDH1A1 | |
| SCHEMBL11251007 | 0.91 | SOS1 (0.40) | NOTUMSOS1CFTRMAPTKDM4E | |
| SCHEMBL11240936 | 0.90 | SOS1 (0.40) | NOTUMSOS1CFTRMAPTKDM4E | |
| SCHEMBL11260601 | 0.89 | SOS1 (0.41) | NOTUMSOS1CFTRKDM4EALDH1A1 | |
| SCHEMBL11262332 | 0.87 | ALDH1A1 (0.32) | CFTRMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL11251640 | 0.86 | SOS1 (0.37) | NOTUMSOS1CFTRKDM4EALDH1A1 | |
| SCHEMBL11249836 | 0.85 | SOS1 (0.36) | NOTUMSOS1CFTRKDM4EALDH1A1 | |
| SCHEMBL11277981 | 0.84 | SDHB (0.39) | NOTUMSOS1CFTRKDM4EALDH1A1 | |
| SCHEMBL11248479 | 0.84 | SOS1 (0.36) | NOTUMSOS1CFTRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314844-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1982-02-09 | — | — | US | disclosed |