Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 8/20 | 0.43 |
| ▸ | CTSD | P07339 | 2/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | NMT2 | O60551 | 1/20 | 0.41 |
| ▸ | NMT1 | P30419 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30361224 | 0.99 | FOLH1 (0.50) | FOLH1BACE1CTSDDPP8DPP9 | |
| SCHEMBL11087895 | 0.93 | FOLH1 (0.56) | FOLH1BACE1CTSDBACE2CPB2 | |
| SCHEMBL11111912 | 0.92 | FOLH1 (0.48) | FOLH1BACE1CTSDDPP8DPP9 | |
| SCHEMBL11249374 | 0.92 | NOD1 (0.42) | FOLH1BACE1CTSDDPP8DPP9 | |
| SCHEMBL6700436 | 0.91 | GSR (0.45) | FOLH1BACE1CTSDDPP8DPP9 | |
| SCHEMBL6700441 | 0.91 | GSR (0.45) | FOLH1BACE1CTSDDPP8DPP9 | |
| SCHEMBL30033871 | 0.91 | BACE1 (0.46) | FOLH1BACE1CTSDBACE2 | |
| SCHEMBL29460689 | 0.90 | FOLH1 (0.49) | FOLH1BACE1CTSDDPP8DPP9 | |
| SCHEMBL29776755 | 0.90 | GSR (0.44) | FOLH1BACE1CTSDDPP8DPP9 | |
| SCHEMBL28081108 | 0.90 | BACE1 (0.48) | FOLH1BACE1CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361673-A | TREATMENT OF IMMUNE DEFICIENCIES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-11-30 | — | — | US | disclosed |
| EP-0048573-A2 | Polypeptides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-03-31 | — | — | EP | disclosed |