Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11262102 | 0.88 | MAPK1 (0.43) | MAPK1MEN1KMT2AHTTPOLB | |
| SCHEMBL11261135 | 0.83 | CYP1A2 (0.34) | POLBCA1CA2 | |
| SCHEMBL11254460 | 0.82 | HTT (0.44) | MAPK1MEN1KMT2AHTTPOLB | |
| SCHEMBL11050943 | 0.81 | HTT (0.44) | MAPK1MEN1KMT2AHTTPOLB | |
| SCHEMBL11260929 | 0.80 | KMT2A (0.50) | MAPK1MEN1KMT2AHTTPOLB | |
| SCHEMBL11052110 | 0.78 | MEN1 (0.55) | MAPK1MEN1KMT2AHTTPOLB | |
| SCHEMBL11053819 | 0.78 | KMT2A (0.46) | MAPK1MEN1KMT2AHTTPOLB | |
| SCHEMBL11048661 | 0.78 | MAPK1 (0.52) | MAPK1MEN1KMT2AHTTPOLB | |
| SCHEMBL11056651 | 0.77 | HTT (0.51) | MAPK1MEN1KMT2AHTTPOLB | |
| SCHEMBL11056791 | 0.77 | MAPK1 (0.47) | MAPK1MEN1KMT2AHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326074-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |