Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11059010 | 0.90 | MEN1 (0.55) | KMT2AMAPK1MEN1HTTPOLB | |
| SCHEMBL11265410 | 0.85 | KMT2A (0.56) | KMT2AMAPK1MEN1HTTPOLB | |
| SCHEMBL11262102 | 0.83 | MAPK1 (0.43) | KMT2AMAPK1MEN1HTTPOLB | |
| SCHEMBL11052077 | 0.83 | MEN1 (0.74) | KMT2AMAPK1MEN1POLBLMNA | |
| SCHEMBL11050902 | 0.83 | MAPK1 (0.49) | KMT2AMAPK1MEN1HTTPOLB | |
| SCHEMBL11059026 | 0.82 | RAB9A (0.47) | KMT2AMAPK1MEN1HTTPOLB | |
| SCHEMBL11250511 | 0.81 | CYP1A2 (0.40) | KMT2AMAPK1MEN1POLBLMNA | |
| SCHEMBL11053981 | 0.81 | PDK1 (0.50) | KMT2AMAPK1MEN1HTTPOLB | |
| SCHEMBL11052114 | 0.81 | PDK1 (0.50) | KMT2AMAPK1MEN1HTTPOLB | |
| SCHEMBL11249398 | 0.80 | MAPK1 (0.41) | KMT2AMAPK1MEN1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326074-A | ANTIDIARRHEA AGENTS | WILLIAM H. RORER, INC. (US) | 1982-04-20 | — | — | US | disclosed |