Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.56 |
| ▸ | RARA | P10276 | 8/20 | 0.56 |
| ▸ | RARG | P13631 | 6/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11249456 | 1.00 | RARB (0.56) | RARBRARARARGPPARGCA12 | |
| SCHEMBL7547910 | 0.84 | RARB (0.59) | RARBRARARARGCYP26A1LMNA | |
| SCHEMBL7547905 | 0.84 | RARB (0.59) | RARBRARARARGCYP26A1LMNA | |
| SCHEMBL9717141 | 0.80 | CA1 (0.66) | PPARGCA12CA1CA2CA7 | |
| SCHEMBL9717146 | 0.80 | CA1 (0.66) | PPARGCA12CA1CA2CA7 | |
| SCHEMBL10618582 | 0.80 | CA1 (0.66) | PPARGCA12CA1CA2CA7 | |
| SCHEMBL4799160 | 0.80 | RARA (0.56) | RARBRARARARGPPARGCA12 | |
| SCHEMBL4799144 | 0.80 | RARA (0.56) | RARBRARARARGPPARGCA12 | |
| SCHEMBL10846840 | 0.79 | RARA (0.72) | RARBRARARARGPPARGCA12 | |
| SCHEMBL10845484 | 0.79 | RARB (0.53) | RARBRARARARGCYP26A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326055-A | ANTITUMOR AGENTS, SKIN DISORDERS, RHEUMATIC DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1982-04-20 | — | — | US | disclosed |