Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 5/20 | 0.63 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246840 | 0.79 | HCAR3 (0.97) | HCAR3TP53TSHR | |
| Hydrochloric Acid SCHEMBL11180843 | 0.78 | HCAR3 (0.94) | HCAR3TP53TSHR | |
| SCHEMBL11184789 | 0.77 | HCAR3 (0.72) | HCAR3MGLLDEGS1CNR2 | |
| SCHEMBL11253069 | 0.74 | HCAR3 (0.60) | HCAR3DEGS1CNR2TSHRRAB9A | |
| SCHEMBL27418247 | 0.74 | HCAR3 (0.55) | HCAR3RAB9AMAPTKMT2A | |
| SCHEMBL1680894 | 0.73 | HCAR3 (0.76) | HCAR3CNR2 | |
| SCHEMBL22265370 | 0.73 | HCAR3 (0.59) | HCAR3CNR2RAB9AMAPT | |
| SCHEMBL22047713 | 0.73 | HCAR3 (1.00) | HCAR3CNR2 | |
| SCHEMBL11257156 | 0.73 | HCAR3 (0.58) | HCAR3DEGS1CNR2RAB9AMAPT | |
| SCHEMBL9646713 | 0.72 | PTK2 (0.56) | DEGS1TSHRRAB9AMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013153-B1 | 6-AMINO PYRIDINE CARBOXYLIC ACID DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1982-12-22 | — | — | EP | claimed |