Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 10/20 | 0.62 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29607767 | 0.84 | ERN1 (0.60) | ERN1HTTLMNAMEN1KMT2A | |
| SCHEMBL6981731 | 0.84 | ERN1 (0.60) | ERN1HTTLMNAMEN1KMT2A | |
| SCHEMBL38660601 | 0.83 | ERN1 (0.53) | ERN1HTTLMNAMEN1KMT2A | |
| SCHEMBL12697422 | 0.81 | GPR35 (0.51) | ERN1HTTLMNAMEN1KMT2A | |
| SCHEMBL8114375 | 0.81 | ERN1 (0.56) | ERN1HTTLMNAMEN1KMT2A | |
| SCHEMBL14113093 | 0.81 | ALDH1A1 (0.57) | ERN1HTTLMNAMEN1KMT2A | |
| SCHEMBL31046602 | 0.81 | ERN1 (0.56) | ERN1HTTLMNAMEN1KMT2A | |
| SCHEMBL8125144 | 0.81 | ERN1 (0.51) | ERN1HTTLMNAMEN1KMT2A | |
| SCHEMBL6981282 | 0.81 | ERN1 (0.56) | ERN1HTTLMNAMEN1KMT2A | |
| SCHEMBL8125146 | 0.80 | ERN1 (0.50) | ERN1HTTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012079-B1 | SPIROPYRANE DERIVATIVES OF PIPERIDINE OR THIAZINE CYCLES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN PHOTOCHROMIC COMPOSITIONS | ETAT-FRANCAIS représenté par le Délégué Général pour l' Armement (FR) | 1982-09-29 | — | — | EP | disclosed |
| EP-0012079-A1 | Spiropyrane derivatives of piperidine or thiazine cycles, process for their preparation and their use in photochromic compositions | ETAT-FRANCAIS représenté par le Délégué Général pour l' Armement (FR) | 1980-06-11 | — | — | EP | disclosed |