Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29068022 | 0.85 | GRM2 (0.43) | KMT2AALDH1A1POLBTLR8 | |
| SCHEMBL15888096 | 0.78 | ALDH1A1 (0.41) | KMT2AALDH1A1POLBBRD4TLR8 | |
| SCHEMBL28941744 | 0.77 | BRD4 (0.34) | KMT2AALDH1A1POLBBRD4TLR8 | |
| SCHEMBL12636575 | 0.77 | FPR2 (0.46) | KMT2AALDH1A1POLBMAPTLMNA | |
| SCHEMBL923857 | 0.76 | KMT2A (0.36) | KMT2AALDH1A1POLBBRD4TLR8 | |
| SCHEMBL926457 | 0.76 | KMT2A (0.36) | KMT2AALDH1A1POLBBRD4TLR8 | |
| SCHEMBL9965487 | 0.76 | TLR8 (0.38) | KMT2AALDH1A1POLBBRD4TLR8 | |
| SCHEMBL923418 | 0.76 | MAPT (0.37) | KMT2AALDH1A1POLBTLR8MAPT | |
| SCHEMBL1888098 | 0.76 | FPR2 (0.40) | KMT2AALDH1A1POLBMAPTLMNA | |
| SCHEMBL996478 | 0.74 | BRD4 (0.43) | KMT2AALDH1A1POLBBRD4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348518-A | Cephalosporins | HOFFMANN-LA ROCHE INC. (US) | 1982-09-07 | — | — | US | disclosed |
| US-4091211-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1978-05-23 | — | — | US | disclosed |