⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29243927 | 0.81 | — | — | |
| SCHEMBL3182700 | 0.75 | — | — | |
| SCHEMBL28339668 | 0.72 | — | — | |
| SCHEMBL1087364 | 0.64 | — | — | |
| SCHEMBL28782674 | 0.62 | — | — | |
| SCHEMBL8836486 | 0.62 | — | — | |
| SCHEMBL16859715 | 0.61 | ALDH1A1 (0.31) | — | |
| SCHEMBL1087491 | 0.59 | — | — | |
| SCHEMBL7949791 | 0.59 | — | — | |
| SCHEMBL28017556 | 0.59 | GLS (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4365074-A | ACRYLIC ESTER COPOLYMERS | Tsuetaki, George F. (US) | 1982-12-21 | — | — | US | disclosed |
| US-4314068-A | Oxygen-permeable contact lens compositions, methods, and articles of manufacture | Tsuetaki, George F. (US) | 1982-02-02 | — | — | US | disclosed |
| US-4216303-A | Oxygen-permeable contact lens compositions, methods and articles of manufacture | Tsuetaki, George F. (US) | 1980-08-05 | — | — | US | disclosed |