SCHEMBL11250396

SCHEMBL11250396

N#Cc1cn(-c2c(Cl)cccc2Cl)c(=O)[nH]c1=O

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.56
L3MBTL1 Q9Y468 1/20 0.51
KMT2A Q03164 4/20 0.50
MEN1 O00255 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.44
GRIA1 P42261 1/20 0.41
CACNG8 Q8WXS5 1/20 0.41
HCAR1 Q9BXC0 1/20 0.38
KDM4E B2RXH2 4/20 0.38
DYRK1A Q13627 1/20 0.36
ALDH1A1 P00352 4/20 0.36
HPGD P15428 3/20 0.36
GALR3 O60755 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
MAPT P10636 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
MCL1 Q07820 1/20 0.34
DPYD Q12882 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11243717 0.90 GAA (0.56) GAAL3MBTL1KMT2AMEN1SMN1; SMN2
SCHEMBL11242715 0.85 L3MBTL1 (0.48) GAAL3MBTL1KMT2AMEN1SMN1; SMN2
SCHEMBL11260931 0.84 GAA (0.52) GAAL3MBTL1KMT2AMEN1SMN1; SMN2
SCHEMBL11241946 0.84 GAA (0.51) GAAL3MBTL1KMT2AMEN1SMN1; SMN2
SCHEMBL11248200 0.82 GAA (0.56) GAAL3MBTL1KMT2AMEN1SMN1; SMN2
SCHEMBL11245190 0.82 GAA (0.63) GAAL3MBTL1KMT2AMEN1SMN1; SMN2
SCHEMBL11251848 0.82 GAA (0.56) GAAL3MBTL1KMT2AMEN1SMN1; SMN2
SCHEMBL11255394 0.79 L3MBTL1 (0.56) GAAL3MBTL1KMT2AMEN1SMN1; SMN2
SCHEMBL11268199 0.79 GAA (0.56) GAAL3MBTL1KMT2AMEN1SMN1; SMN2
SCHEMBL11248107 0.78 L3MBTL1 (0.61) GAAL3MBTL1KMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4358591-A BACTERICIDES, FUNGICIDES; PLANT DISEASES ZOECON CORPORATION (US) 1982-11-09 US disclosed
US-4338318-A FUNGICIDE OR BACERICIDE TO TREAT PLANT DISEASES WITH A PHENYL URACIL ZOECON CORPORATION (US) 1982-07-06 US disclosed
US-4307098-A 2-PHENYL-URACIL COMPOUNDS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1981-12-22 US disclosed
US-4297297-A α-Cyano-β-(substituted-anilino)-N-ethoxycarbonylacrylamide intermediates ZOECON CORP. (US) 1981-10-27 US disclosed
US-4266056-A FUNGICIDES, BACTERICIDES ZOECON CORPORATION (US) 1981-05-05 US disclosed