SCHEMBL11255394

SCHEMBL11255394

N#Cc1cn(-c2cccc(Cl)c2)c(=O)[nH]c1=O

nearest known ligand 0.68

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.56
KMT2A Q03164 3/20 0.54
MEN1 O00255 2/20 0.54
GAA P10253 2/20 0.53
KDM4E B2RXH2 3/20 0.45
ALDH1A1 P00352 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
HCAR1 Q9BXC0 1/20 0.42
MGLL Q99685 1/20 0.41
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
RXRG P48443 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
XDH P47989 1/20 0.40
LMNA P02545 1/20 0.39
HPGD P15428 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11249006 0.85 L3MBTL1 (0.57) L3MBTL1KMT2AMEN1GAAKDM4E
SCHEMBL11253559 0.84 L3MBTL1 (0.54) L3MBTL1KMT2AMEN1GAAALDH1A1
SCHEMBL11243644 0.84 GAA (0.59) L3MBTL1KMT2AMEN1GAAKDM4E
SCHEMBL11245813 0.84 L3MBTL1 (0.68) L3MBTL1KMT2AMEN1GAAKDM4E
SCHEMBL11248370 0.83 L3MBTL1 (0.67) L3MBTL1KMT2AMEN1GAAKDM4E
SCHEMBL8888929 0.83 L3MBTL1 (0.59) L3MBTL1KMT2AMEN1GAAALDH1A1
SCHEMBL8888355 0.82 L3MBTL1 (0.55) L3MBTL1KMT2AMEN1GAASMN1; SMN2
SCHEMBL11240303 0.82 L3MBTL1 (0.74) L3MBTL1KMT2AMEN1GAAKDM4E
SCHEMBL11251327 0.81 L3MBTL1 (0.54) L3MBTL1KMT2AMEN1GAAKDM4E
SCHEMBL11243353 0.80 KMT2A (0.73) L3MBTL1KMT2AMEN1GAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4338318-A FUNGICIDE OR BACERICIDE TO TREAT PLANT DISEASES WITH A PHENYL URACIL ZOECON CORPORATION (US) 1982-07-06 US disclosed
US-4297297-A α-Cyano-β-(substituted-anilino)-N-ethoxycarbonylacrylamide intermediates ZOECON CORP. (US) 1981-10-27 US disclosed
US-4266056-A FUNGICIDES, BACTERICIDES ZOECON CORPORATION (US) 1981-05-05 US disclosed