Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 4/20 | 0.57 |
| ▸ | ESR1 | P03372 | 2/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 10/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | APEX1 | P27695 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250467 | 1.00 | NR1I2 (0.57) | NR1I2ESR1PPARGPGRADRA1A | |
| SCHEMBL11388440 | 0.94 | ADRA1A (0.57) | NR1I2ESR1PPARGPGRADRA1A | |
| SCHEMBL11347520 | 0.94 | ADRA1A (0.57) | NR1I2ESR1PPARGPGRADRA1A | |
| SCHEMBL11040820 | 0.94 | ADRA1A (0.57) | NR1I2ESR1PPARGPGRADRA1A | |
| SCHEMBL11055209 | 0.93 | KCNH2 (0.62) | NR1I2ESR1PPARGPGRADRA1A | |
| SCHEMBL11366554 | 0.93 | KCNH2 (0.62) | NR1I2ESR1PPARGPGRADRA1A | |
| SCHEMBL11257216 | 0.93 | ADRA1A (0.56) | NR1I2ESR1PPARGPGRADRA1A | |
| SCHEMBL11257219 | 0.93 | ADRA1A (0.56) | NR1I2ESR1PPARGPGRADRA1A | |
| SCHEMBL11059582 | 0.93 | ADRA1A (0.58) | NR1I2ESR1PPARGPGRADRA1A | |
| SCHEMBL9510176 | 0.93 | NR1I2 (0.65) | NR1I2ESR1PPARGPGRADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0047977-A2 | Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and their use | CIBA-GEIGY AG (CH) | 1982-03-24 | — | — | EP | disclosed |