Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL499731 | 0.78 | USP2 (0.48) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL3410000 | 0.77 | PTPN7 (0.44) | — | |
| SCHEMBL7580131 | 0.77 | PTPN7 (0.44) | — | |
| SCHEMBL17998130 | 0.76 | KDM4E (0.35) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL11754274 | 0.75 | KDM4E (0.37) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL9500520 | 0.75 | TSHR (0.61) | NLRP3TSHRKDM4EUSP2ALDH1A1 | |
| SCHEMBL3938270 | 0.74 | — | — | |
| SCHEMBL11280416 | 0.73 | ALDH1A1 (0.38) | TSHRKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL28540663 | 0.73 | RECQL (0.49) | KDM4EUSP2ALDH1A1 | |
| SCHEMBL11399444 | 0.72 | TSHR (0.62) | NLRP3TSHRKDM4EUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315022-A | ANTISECRETORY AGENTS, BRONCHODILATOR AGENTS | BEECHAM GROUP LIMITED (GB) | 1982-02-09 | — | — | US | disclosed |
| EP-0020039-A1 | Imidazole derivatives, their preparation and their pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1980-12-10 | — | — | EP | disclosed |