Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 6/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
| ▸ | BACE1 | P56817 | 4/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11291840 | 0.90 | ALDH1A1 (0.41) | KDM4EKDM1AMAOAMAOBBCHE | |
| SCHEMBL11258364 | 0.89 | DRD2 (0.42) | KDM4EKDM1AMAOAMAOBDRD2 | |
| SCHEMBL11474467 | 0.88 | KDM1A (0.43) | KDM4EKDM1AMAOAMAOBKDM1B | |
| SCHEMBL11474464 | 0.85 | KDM4E (0.45) | KDM4EKDM1AMAOAMAOBKDM1B | |
| SCHEMBL11483314 | 0.85 | KDM4E (0.45) | KDM4EKDM1AMAOAMAOBKDM1B | |
| SCHEMBL11259932 | 0.85 | KDM4E (0.45) | KDM4EKDM1AMAOAMAOBKDM1B | |
| SCHEMBL11246927 | 0.81 | BACE1 (0.42) | KDM4EKDM1AMAOAMAOBDRD2 | |
| SCHEMBL11254474 | 0.78 | KMT2A (0.42) | KDM4EKDM1AMAOAMAOBMEN1 | |
| SCHEMBL11245385 | 0.77 | ALDH1A1 (0.44) | KDM4EKDM1AMAOAMAOBDRD2 | |
| SCHEMBL11245449 | 0.75 | TRPV1 (0.45) | BACE1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001428-B1 | INSECTICIDAL AND ACARICIDAL AGENTS CONTAINING CHROMAN DERIVATIVES, THEIR PREPARATION AND THEIR USE, AS WELL AS CHROMAN DERIVATIVES AND THEIR PREPARATION | BAYER AG (DE) | 1982-03-24 | — | — | EP | disclosed |
| US-4238501-A | INSECTICIDES, MITICIDES, PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | disclosed |
| US-4237162-A | MITICIDES, LARVACIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-02 | — | — | US | disclosed |
| US-4206151-A | BRONCHODILATOR, ANTISECRETORY, HYPOTENSIVE | AMERICAN CYANAMID COMPANY (US) | 1980-06-03 | — | — | US | disclosed |
| EP-0001428-A1 | Insecticidal and acaricidal agents containing chroman derivatives, their preparation and their use, as well as chroman derivatives and their preparation | BAYER AG (DE) | 1979-04-18 | — | — | EP | disclosed |